The Linux kernel supports many additional formats, such as Microsoft's NTFS, the various FAT formats, the old OS/2 HPFS, and Apple's HFS. These formats do not support the attributes required by a Linux system, and are thus not appropriate for a root filesystem. They could be used for other data should it be necessary. Note that these formats lack the basic Linux security attributes, although there is some provision for translating the attributes that do exist into their approximate Linux equivalents.
If you need dedicated infrastructure for flexible software compatibility, consider a Spain Dedicated Server for working with non-Linux formats on Debian systems, managing compatible file systems, and maintaining reliable performance with dedicated resources and full server control.